(200) Inhibition of PAL, CHS, and ERS1 Transcription by 1-MCP
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چکیده
منابع مشابه
MCP-1 induces a novel transcription factor with proapoptotic activity.
Over the past years, the crucial and versatile functions of the prototypic CC chemokine monocyte chemotactic protein-1 (MCP-1/CCL2) and its cognate receptor CCR2 in the recruitment of monocytes/macrophages during atherogenesis and other inflammatory processes in the cardiovascular system have been well established.1,2 Although MCP-1 is not expressed in healthy vessels, various stimuli (eg, tumo...
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Monocyte chemotactic protein-1 (MCP-1) has been recognized as an angiogenic chemokine. The molecular mechanism of MCP-1-mediated angiogenesis remains unknown. We recently identified a novel transcription factor, designated MCP-1-induced protein (MCPIP), in human monocytes after treatment with MCP-1. We investigated whether MCP-1-induced angiogenesis is mediated via MCPIP. Treatment of human umb...
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BACKGROUND/AIMS Experimental and clinical evidence suggested that monocyte chemoattractant protein-1 (MCP-1/CCL2) has a role in the development of interstitial inflammation and renal failure in polycystic kidney disease (PKD). We investigated whether bindarit, an inhibitor of MCP-1/CCL2 synthesis, could influence the evolution of PKD in PCK rats. METHODS PCK rats were treated from 5 to 15 wee...
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Although accumulated evidence supports the notion that mesenchymal stem cells (MSCs) act in a paracrine manner, the mechanisms are still not fully understood. Recently, MSC-derived exosomes (MSC-Exos), a type of microvesicle released from MSCs, were thought to carry functional proteins and RNAs to recipient cells and play therapeutic roles. In the present study, we intravitreally injected MSCs ...
متن کاملInduction of Heme Oxygenase -1 By Lipocalin 2 Mediated By Nf-Kb Transcription Factor
Purpose: Effect of lipocalin 2 on the expression of heme oxygenase I , II and NF-kB transcription factor was the purpose of this survey. Materials and Methods: Lcn2 was cloned to pcDNA3.1 plasmid by using genetic engineering method. The recombinant vector was transfected to CHO and HEK293T to establish stable cell expressing lipocalin 2. The presence of lipocalin 2 gene in these cells was confi...
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ژورنال
عنوان ژورنال: HortScience
سال: 2006
ISSN: 0018-5345,2327-9834
DOI: 10.21273/hortsci.41.4.1051c